During this journal club, we are joined by David Miller, PhD to discuss the results from the HABSelect study, the largest randomized trial of PICSI to date and the first to provide a robust measure of the effect of PICSI on live birth rates. Miller D, et al. Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomized trial. Lancet. 2019;393(10170):416-422. After a short presentation of the study and its findings by Dr Miller, Steven Fleming, PhD will moderate a discussion with the participants in the session.