PGTai

PGTaiSM Technology Platform

Technology platform for embryo selection

PGTai

PGTai Technology Platform

PGTaiSM Technology Platform

Technology platform for embryo selection

Since its launch in 2018, over 350,000 embryos have been tested with our robust PGTai platform1 shown to improve the odds of pregnancy and IVF success2.

Our PGTai is the only test on the market using artificial intelligence (AI) based on clinical outcome data of live births and sustained pregnancy outcomes, eliminating subjectivity, and improving accuracy.

The PGTai platform ​is a ground-breaking, first-of-its-kind mathematical algorithm that harnesses the power of AI, big data, and machine learning to maximize both sensitivity and specificity during PGT-A​.

PGTai Technology Platform

Data is generated via NGS

Data is analyzed using mathematical algorithms & machine learning technology
Our new technology uses algorithms validated through a massive
continuously growing data set(~10,000 samples)

Removes human subjectivity
Avoids human errors

The PGTai platform brings the power of big data
to the clinician’s transfer decisions

PGT Complete white paper

Key Product Information

A history of PGT-A at CooperSurgical

1993
Dr. Santi Munné is the first to present reports on the use of FISH for PGT-A, assessing abnormalities on chromosomes X, Y, 13, 18 and 21

1999
The first use of CGH for PGT-A is reported

2001
The first birth after PGT-A by CGH is reported

2013
Legacy CooperGenomics companies are the first to launch PGT-A by NGS for clinical use

PGTai Technology Platform

2018
CooperGenomics launches the PGTai platform, a first-of-its-kind platform that uses artificial intelligence to improve PGT-A analysis & reporting

2019
CooperGenomics launches the PGTai 2.0 platform, the first PGT-A analysis with secondary confirmation of aneuploidy

2022
CooperGenomics releases the addition of Parental QC, Genetic PN check and Origin of Aneuploidy to PGT-A testing as PGT-Complete

The only platform in the field:​

  • Built on embryo biopsy data (>1000) resulting in live births and sustained pregnancy outcomes​
  • Validated using sequencing data from >10,000 embryos, analyzed and reviewed one by one for accuracy​

Delivering:​

  • Statistically robust and accurate interpretation​
  • Improved analytics by removing subjectivity​
  • Avoids human errors with transcription​
  • Improved signal clarity, to increase accuracy and ensure optimal sensitivity and specificity

PGTai-baby

Built on data of >1000 embryo biopsies with known live birth/sustained pregnancy outcomes

PGTai-head

Eliminates subjectivity in favour or algorithims

PGTai-antennae

Improves signal clarity, increases accuracy and ensures optimal sensitivity and specificity

PGTai-embryo

Increased number of euploid embryos reported, increased percentage of patients with greater that 1 euploid embryo reported

Since introducing PGTai

7.7%
relative increase in euploid embryo reporting

21.2%
relative decrease in mosaic embryo reporting

4.2%
relative decrease in aneuploid embryo reporting

More patients with at least one euploid embryo

PGTaiGraph

Most robust assessment of embryos in the market; providing greater confidence in embryo transfers

  • Two independent methods for confirming abnormality (unique to CooperSurgical
  • Detection of all forms of ploidy – Haploidy, male and female triploidy
  • Parent of origin of abnormality (optional)

Genomics-Strip

Paired-end sequencing increases the amount and quality of data generated from each sample

Provides double coverage and enhances coverage of hard-to-sequence regions

Improves read alignment and availability (>15%)

Allows for highly sensitive analysis

DNAfragment-top

Alignment to the Reference Sequence
DNAfragment-bottom

Genomics-Strip

Read our white papers to find out more about the development of our PGTai technology platform:

PGT-A-iconDownload our PGT-A via:
PGTai Technology Platform
White Paper

PGTai""Download our PGT-A via:
PGTai 2.0 Technology Platform
White Paper

Explaining our PGTai platform to your patients

Our latest video gives your patients a visual guide helping them to understand how PGTai can help them identify an embryo for transfer.

Documents