SAGE 1-Step™

A single step medium for uninterrupted embryo culture

The information below represents the SAGE 1-Step HSA containing hyaluronan.

SAGE 1-Step SPS does not contain hyaluronan, please see the datasheet for SAGE  1-Step SPS for information concerning this product.

SAGE 1-Step is a continuous culture medium that has been developed with a strong focus on robustness. It allows uninterrupted culture following IVF or ICSI insemination through to the blastocyst stage, and is ideal for use with time lapse technology.

Key Features

  • Hyaluronan to promote cryo survival and embryo implantation
  • A stable glutamine source supporting a reduced ammonium build-up
  • Optimized ionic composition and energy substrates supporting uninterrupted continuous culture

Availability

SAGE 1-Step HSA is available for sale in Europe, the U.S.A, Canada and Australia as well as selected countries in the rest of the world.
SAGE 1-Step SPS is available for sale in the U.S.A and selected countries in the rest of the world. It is not available for sale in Europe.

 

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Key Product Information

Product Data Sheet

Instruction for Use

Safety Data Sheet

Order Codes

Brochures

Batch Certificate

Quality Certificates

Order Codes

Reference Description Size HSA mg/ml SPS mg/ml Shelf Life Guarantee*
67010010 SAGE 1-Step™, with HSA and phenol red 10 ml 5 mg/mL – Minimum 8 weeks
67010060 SAGE 1-Step™, with HSA and phenol red 60 ml 5 mg/mL – Minimum 8 weeks
67020010 SAGE 1-Step™, with SPS and phenol red 10 ml – 5 mg/mL Minimum 8 weeks
67020060 SAGE 1-Step™, with SPS and phenol red 60 ml – 5 mg/mL Minimum 8 weeks

*Minimum time to expiry

Product Data Sheet – with HSA
Product Data Sheet – with SPS

with HSA – Instruction for use: Europe
with HSA – Instruction for use: USA/Canada
with HSA – Instruction for Use: Australia
with SPS – Instruction for use: USA/Canada

Safety Data Sheet – SAGE 1-Step with HSA
Safety Data Sheet – SAGE 1-Step with SPS

SAGE 1-Step™ media: DGM 822
SAGE media incorporating HSA and/or gentamicin sulfate: BSi – CE 551319

Embryo Biopsy Brochure
Embryo Biospy Brochure – USA
Embryo Culture Guide
Embryo Culture Guide – USA

  • Magnesium sulphate
  • Potassium chloride
  • Potassium phosphate
  • Sodium chloride
  • Amino acids
  • L-alanyl-L-glutamine
  • Calcium-L-lactate
  • Glucose · Sodium pyruvate
  • Sodium bicarbonate
  • EDTA · Gentamicin
  • Phenol red

SAGE 1-Step™ with HSA (6701) only:

  • Sodium hyaluronate
  • Human Serum Albumin

SAGE 1-Step™ with SPS (6702) only:

  • Serum Protein Supplement (SPS)

  • CE marked (CE 0543): SAGE 1-Step with HSA only
  • Cleared by the FDA
  • Canada Medical Device licensed

  • Sterility tested (Ph. Eur., USP)
  • Osmolality tested (Ph. Eur., USP)
  • pH tested (Ph. Eur., USP)
  • Endotoxin tested ≤ 0.15 EU/ml (Ph. Eur., USP)
  • Mouse Embryo Assay (MEA)