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PICSI® Dish and SpermSlow™ Media

Steve Fleming PhD – Director of Embryology, CooperSurgical

New research on Andrology has been published!

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This white paper by Steve Fleming PhD discusses two different but related approaches developed for sperm selection via their ability to bind Hyaluronan: the PICSI® Dish and SpermSlow™ Media.

“This is an important study which demonstrates the clinical value of sperm selection using the PICSI dish”

Steve Fleming PhD

In this paper, you’ll learn more about:

  • How standard ICSI enables incompetent spermatozoa to bypass the oocyte’s natural gatekeepers which would otherwise help to police sperm quality.
  • The correlation of sperm maturity, decreased aneuploidy, increased chromatin integrity, and decreased sperm DNA fragmentation with the ability of spermatozoa to bind to HA.
  • How ICSI operators only have sperm motility and morphology to assist them in selecting sperm, which provides little indication of the sperm’s genomic integrity.
  • How sperm selection using a PICSI dish significantly reduces the miscarriage rate and improves live birth outcomes among older couples.

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